Squalane, phytosqualane

Description

Natural active emollients – squalane, phytosqualane, squalene

Squalene (SQUAPURE®)
Squalene is an unsaturated natural hydrocarbon classified as a carotenoid. Natural squalene is obtained from animal and plant sources. Since squalene is susceptible to oxidation, a more stable form, squalane, is used in the production of creams and ointments.

Squalane (SOPHIDERM®), phytosqualane (PHYTOSQUALAN®)
Squalane is obtained from natural squalene by hydrogenation. Squalane is a clear, colorless and odorless oil, highly stable and excellently adapted for use in cosmetics and pharmaceuticals.

From a dermatological point of view, squalane is a high-quality emollient (softening agent). Thanks to its natural affinity for the skin, it easily penetrates the epidermis without leaving a greasy feeling, while leaving the skin feeling soft and silky. Squalane is non-comedogenic, unlike triglycerides and fatty acids in sebum.

When applied to the skin, squalane is easily distributed, forming a protective film that prevents moisture loss, which, in turn, helps improve skin respiration. Due to its high stability and low chemical activity, squalane does not react with the active substances of the formulas.
Squalane does not participate in metabolism and is excreted from the body unchanged naturally.

Properties of squalane:

  • Prevents TEWL and restores skin water balance.
  • Distributes quickly and well on the skin.
  • Accelerates wound healing and prevents scarring.
  • Slows down the formation of wrinkles.
  • Protects against the effects of free radicals (recognized as an antioxidant).
  • Protects against photoaging (prevents skin damage from ultraviolet radiation).
  • Carrier of active ingredients.
  • Helps create nano-emulsions.
  • Non-toxic, hypoallergenic.
  • Safety.

The absolute safety of squalane was confirmed by a series of toxicological tests: LD50 > 20ml/kg.
Squalane does not have any adverse effects when used in formulations intended for use on all areas of the body: skin, hair, mucous membranes, eyes, nails, etc. There were also no negative interactions between fragrances and squalane.

Applications of squalane:

  • medicinal creams;
  • dermatological creams;
  • cosmetic creams;
  • sunscreens;
  • hair care products;
  • face masks.

Benefits of using squalane:

  • Due to its high stability and low chemical activity, squalane does not interact with the active substances of the formulas.
  • Fully compatible with oils and lipophilic substances, squalane can be easily emulsified to create attractive, compact and shiny emulsions.
  • Squalane is absolutely stable and resistant to oxidation.
  • Squalane is of interest for formulations in which a necessary condition is to preserve the appearance and quality of the drug at low temperatures, because it has a low pour point.
  • Added to cosmetics as a softening and bactericidal component.
  • Restores damaged skin after chemical peels, microdermabrasion procedures and other aggressive factors affecting the skin.
  • Squalane is an excellent dispersant for pigments (in decorative cosmetics) as well as titanium dioxide (UV filters).
  • Due to its ability to regulate the diffusion of fragrant substances, squalane can be used as a fragrance fixative.

Specifications

Table of offered products

Trademark The product’s name Description Purpose
PHYTOSQUALAN® Squalane Vegetable squalane from olive, pure, odorless, colorless
ECOCERT
Active ingredient, bioactive emollient, humectant, pigment dispersant and TiO2 (titanium dioxide)
SOPHIDERM® Squalane Squalane of animal origin (from shark liver), pure, odorless, colorless
Pharm quality
Active ingredient, bioactive emollient, humectant, pigment dispersant and TiO2 (titanium dioxide)
SQUAPURE® Squalene Animal squalene (from shark liver)
Farm quality
Active ingredient, bioactive emollient, humectant

 

Specifications

SQUAPURE® SOPHIDERM® PHYTOSQUALAN®
Specific Gravity 0.845 – 0.865°C, g/ml 0.807 – 0.810°C, g/ml 0.810 – 0.820°C, g/ml
Refractive index 1.4945 – 1.4965 1.4510 – 1.4525 1.4520 – 1.4580
Iodine number 360-380 1.0 max 4.0 max
Saponification number 1.0 max 1.0 max 3.0 max
Acid value 1 max 0.2 max 0.5 max
Purity by gas chromatography 99%min 99%min 92% min

 

Recommendations for use:
It has an important advantage – thermal stability.
Squalane is added to creams and ointments in the same way as other oils at production temperatures (up to 96°C).

The amount of squalane added to formulations varies widely. Some formulations use less than 1%, while others use more than 50%. The optimal level is 5 – 15%.

Solubility: Squalane is soluble in mineral oils, vegetable oils and non-polar solvents. It is insoluble in polar solvents.

Compatibility: Squalane is compatible with other major products used in formulations. No reaction of other components with them was detected.

Packaging: 5 kg; 10 kg; 25 kg; 180 kg.

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