Selenium disulfide

Selenium disulfide (SeS₂) is a binary inorganic compound of selenium and sulfur. It is obtained by the action of hydrogen sulfide on a solution of selenous acid. It has a yellowish-red color. Does not dissolve in water.

Description

Selenium disulfide (SeS₂) is a binary inorganic compound of selenium and sulfur. It is obtained by the action of hydrogen sulfide on a solution of selenous acid. It has a yellowish-red color. Does not dissolve in water.

pharmachologic effect

It has a pronounced antifungal and antiseborrheic effect.
Selenium disulfide, when applied to the skin, has a triple effect:

  • Cytostatic – regulates the process of renewal of epidermal cells by normalizing the function of the sebaceous glands.
  • Fungicidal – inhibits the growth of yeast fungi of the genus Malasseria and destroys the environment favorable for their excessive reproduction.
  • Keratolytic – normalizes the exfoliation of dead epidermal cells and prevents the appearance of dandruff.

Mechanism of action

Selenium disulfide blocks the growth of epidermal cells and epithelial follicles, reduces the production of corneocytes. The selenium disulfide molecule, attaching to the cell wall of the fungus, prevents its division and, therefore, reproduction.

Application

Dermatomycoses, especially pityriasis versicolor, seborrheic dermatitis of the scalp, dandruff, seborrheic psoriasis, folliculitis.
Selenium disulfide can be used in cosmetics such as shampoos, pastes, creams and soaps.

Latest developments for application

Selenium disulfide can be used in products for the care of problematic and oily skin of the face and body, prone to the formation of pimples and acne, as it regulates the functioning of the sebaceous glands, reducing the secretion of sebum (sebum), and effectively inhibits the activity of Propionibacterium bacteria Acnes, which provokes the formation of pimples and acne on the skin, prevents the formation of comedones and has a good drying and cleansing effect.
Selenium shampoo for dogs is an excellent drug for use during the treatment of skin diseases such as dry seborrhea (dandruff), itching, excessive peeling or redness. The shampoo effectively removes even heavy impurities from the skin surface and restores the natural softness and shine of the hair.

Features of application

The presence of selenium disulfide in shampoos is strictly limited: the permissible dose of selenium disulfide is no more than 1%. The use of leave-in products containing this component is not recommended. Use only for external use.

Specification

Description Fine powder ranging from bright brown to bright orange in color and with a faint odor
Solubility Practically soluble in water and organic solvents
Compliance with pharmacopoeia EP/USP
Contents Selena 52-55%
Residue after calcination 0.2%
Particle size 90% < 10 micrometers
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